Serum immunoglobulin D and malaria antibodies in South Vietnamese residents☆

Serum immunoglobulin D concentrations were found to be elevated in Vietnamese and Montagnard but not in Cambodian residents of a Vietnam village which is highly endemic for malaria. Although a high frequency of positive malaria CF tests was demonstrated in all three groups, there was no significant correlation between the serum IgD levels and the malaria CF titres. Serum IgD levels in Vietnamese residents of a non-malarious community were similar to those of United States blood donors, however, in the former groups, a high frequency (i.e., 90%) of low titre CF reactions was observed, compared to a frequency of 8% low titre CF reactions in the U.S. donors.